Reconstituting and Powering Cell Division

演題

Reconstituting and Powering Cell Division

講演者

Dr. Mohan K. Balasubramanian (Director, Institute of Advanced Study Professor, Warwick Medical School Centre for Mechanochemical Cell Biology, Division of Biomedical Sciences University of Warwick, U.K.)

使用言語

English

日時

2023年11月2日(木曜日) 15：00～16：00

場所

L12 meeting room

内容

Two trillion cells divide every day in the human body, each one requiring a force-generating contractile actomyosin ring. CAR-based cytokinesis occurs widely in metazoans, fungi, and amoeba. The CAR assembles between segregated chromosomes and its constriction actuates division of one cell into two. The CAR is a highly dynamic device, with its core built from ~250,000 protein molecules (~100 different proteins), assembled precisely before cytokinesis and disassembled concomitantly with CAR constriction. In my talk, I will discuss the questions of what powers cell division, how the CAR contributes to force generation, and how CAR constriction drives PM ingression and division septum assembly.

問合せ先

Gene Regulation Research
Bessho Yasumasa (ybessho@bs.naist.jp)