Mathematical proof of biologists' intuition by a stochastic theory

演題

Mathematical proof of biologists' intuition by a stochastic theory

講演者

Dr. Henri Jimbo (Department of Molecular Biology, Graduate School of Biological Sciences, NAIST)

使用言語

English

日時

2010年5月24日(月曜日) 13：30～

場所

バイオサイエンス研究科 大セミナー室

内容

In biological system, order is built from disorderly behaving components. For example, it is well established that the expression of genes is noisy, which contributes to building a less noisy structure such as a cell. This fact has been observed and known for many years and has become a major intuition of biologists. However, a unifying theory to explain how order is established from noisy components has been a decades-long question in biological science. As a step toward to building such a theory, we have applied a stochastic theory to provide a formal mathematical proof to this long-standing biologists' intuition. Our results here provide a quantitative proof that order could be built from noisy regulatory components. Furthermore, our findings indicate that many, if not all, biological processes, even those that appear to be governed by deterministic mechanisms, could be explained by a stochastic theory. In conclusion, we propose that re-evaluating all biological processes based on such stochastic theory may lead to inventing a new biological law.

問合せ先

生体機能制御学
佐藤 匠徳 (island1005@bs.naist.jp)