セミナー情報

セミナー情報

From Protein Folding to Cognition: a Serendipitous Path of Discovery

演題 From Protein Folding to Cognition: a Serendipitous Path of Discovery
講演者 Dr. Peter Walter (University of California, San Francisco)
使用言語 英語
日時 平成29年6月6日(火曜日) 11:00~12:30
場所 大セミナー室
内容 A screen for small molecule modulators of the unfolded protein response yielded ISRIB, a drug-like compound that with high efficacy renders cells insensitive to translational inhibition by phosphorylation of eIF2. ISRIB is an activator of eIF2B, eIF2’s guanine nucleotide exchange factor, and a cognitive enhancer in rodents, significantly improving long-term memory of wild-type animals in behavioral assays.
問合せ先 ストレス微生物科学
木俣 行雄 (kimata@bs.naist.jp)

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