Functional Dissection of LRR-Kinase Receptors and Plant Defense Signaling.
|演題||Functional Dissection of LRR-Kinase Receptors and Plant Defense Signaling.|
|講演者||Prof. Andrew Bent (Department of Plant Pathology, University of Wisconsin - Madison)|
We are investigating multiple topics related to plant disease resistance and to the functional mechanics of proteins with LRR (leucine-rich repeat) domains. We have been studying FLS2, a transmembrane LRR-kinase protein that is the plant receptor of bacterial flagellin, as well as EFR, the plant receptor LRR-kinase for bacterial EF-Tu. Our dissection of specific receptor sub-domains and their contributions to signaling and to protein-protein interactions will be discussed. An algorithm will be described that detects regions of conservation on the predicted surface of folded LRR domains as a means to identify candidate functional domains within the LRR. Lastly, or work on the roles of poly(ADP-ribosyl)ation in the defense signaling pathways elicited by flagellin or EF-Tu will be described.<References (but note: I will talk primarily about unpublished work)>
島本 功 (firstname.lastname@example.org)