Molecular mechanisms linking Zika virus replication and neuropathogenesis

演題

Molecular mechanisms linking Zika virus replication and neuropathogenesis

講演者

Dr. Priya S. Shah (Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis)

使用言語

English

日時

2024年1月10日(水曜日) 11：00～12：00

場所

Online

内容

The Shah Lab studies virus-host interactions using quantitative systems biology approaches. In this seminar, we travel from large-scale protein interaction networks to amino acid resolution to unravel molecular mechanisms of viral replication and disease. We discuss how a single protein interaction between Zika virus non-structural protein 4A (NS4A) and human Ankyrin repeat LEM domain containing 2 (ANKLE2) facilitates virus replication and neuropathogenesis, and our efforts to uncouple the two.

 

問合せ先

Molecular Immunology
Taro Kawai (tarokawai@bs.naist.jp)