セミナー情報

セミナー情報

Molecular Mechanisms in Plant Natural

演題 Molecular Mechanisms in Plant Natural
講演者 Dr. Juergen Ehlting (University of Victoria)
使用言語 English
日時 平成24年2月14日(火曜日) 15:20~16:00
場所 大セミナー室
内容
Metabolic plasticity, which largely relies on the creation of new genes, is an essential feature of plant adaptation and speciation and has led to the evolution of large gene families. A typical example is provided by the diversification of the cytochrome P450 enzymes in plants. We describe here a retroposition, neofunctionalization, and duplication sequence that, via selective and local amino acid replacement, led to the evolution of a novel phenolic pathway in Brassicaceae. This pathway involves a cascade of six successive hydroxylations by two partially redundant cytochromes P450, leading to the formation of N1,N5-di(hydroxyferuloyl)-N10-sinapoylspermidine, a major pollen constituent and so-far-overlooked player in phenylpropanoid metabolism. This example shows how positive Darwinian selection can favor structured clusters of nonsynonymous substitutions that are needed for the transition of enzymes to new functions.

Reference:
Matsuno M. et al. (2009) Evolution of a novel phenolic pathway for pollen development. Science 325: 1688-1692

問合せ先 植物代謝調節学
出村 拓 (demura@bs.naist.jp)

一覧へ戻る