Single-cell and spatial dissection of plant-microbe interactions​

Title Single-cell and spatial dissection of plant-microbe interactions​
Lecturer Dr. Tatsuya Nobori, (The Salk Institute, CA USA)
Language English
Date&Time 09/27/2023 (Wed) 15:00~16:00
Venue Rethink Biological Science Seminar Hall(L11)

In multicellular organisms, individual cells interpret a multitude of developmental and environmental signals through unique gene regulatory mechanisms, leading to highly diverse cellular responses. A comprehensive understanding of tissue function necessitates investigating these complex gene regulatory patterns within individual cells, all while maintaining the native three-dimensional (3D) tissue context. In this seminar, I will cover two main topics: (1) the use of single-cell multiomics and spatial transcriptomics in studying the model plant Arabidopsis thaliana, and (2) the development of PHYTOMap, a novel method for multiplexed single-cell 3D spatial gene expression analysis in whole-mount plant tissue. I will discuss how the integration of these methodologies allows for unprecedented resolution in studying plant-microbe interactions.​


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