Outline of Research and Education
We are interested in the holistic view of gene regulation in plant reproduction, which leads to developmental robustness and coordination. We explore signaling and epigenetic control in stem cell maintenance, environmental response and fertilization. To reveal the molecular mechanisms, we use Arabidopsis as a model plant for genetic, reverse-genetic, biochemical and genomics approaches, as well as Brassicas and rice to study the conservation and diversification. Our students work at the frontiers of plant molecular genetics, developing their research, presentation and writing skills.
Major Research Topics
Floral stem cell homeostasis
Flowers originate from self-renewing pluripotent stem cells in the floral meristems (Fig.1). The maintenance and differentiation of stem cells are regulated by a well-coordinated interplay of cell-cell signaling and epigenetic regulation, leading to spatiotemporal-specific gene regulation. We study downstream cascades of the receptor kinase signaling pathway controlling stem cell homeostasis.
Stem cell termination and cell specification
In flower development, the stem cell activity is terminated in multistep pathways mediated by multiple transcription factors. We study transcriptional/epigenetic mechanisms and hormone signaling controlling stem cell termination and cell specification (Fig. 2).
Environmental response and acclimation
We study how plants memorize environmental temperature and light conditions and reveal the molecular mechanisms that confer the plasticity and robustness of the cascades under various environmental stimuli. These studies will serve as the basis of plant growth optimization for better yields of crop plants (Fig.3).
Mechanisms of dominant/recessive relationships in plants
Pollen determinant genes functioning for self-incompatibility is governed by a complex dominance hierarchy. We study the mechanism of this dominant/recessive relationships regulated by small RNA-based epigenetic mechanism and its evolution in Brassicaceae.
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