- Development of a green reversibly photoswitchable variant of Eos fluorescent protein with fixation resistance.
Osuga M, Nishimura T, Suetsugu S.
Mol Biol Cell. 2021 Nov 1;32(21):br7. doi: 10.1091/mbc.E21-01-0044. - FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells.
Kamasaki T, Miyazaki Y, Ishikawa S, Hoshiba K, Kuromiya K, Tanimura N, Mori Y, Tsutsumi M, Nemoto T, Uehara R, Suetsugu S, Itoh T, Fujita Y.
iScience. 2021 Aug 18;24(9):102994. doi: 10.1016/j.isci.2021.102994. - Translation of cellular protein localization using convolutional network.
Shigene K, Hiasa Y, Otake Y, Soufi M, Janewanthanakul S, Nishimura T, Sato Y, Suetsugu S.
Front Cell Dev Biol. 2021 Aug 5;9:635231. doi: 10.3389/fcell.2021.635231.
プレスリリース English - Dynamin 2 and BAR domain protein pacsin 2 cooperatively regulate formation and maturation of podosomes.
Li J, Fujise K, Wint H, Senju Y, Suetsugu S, Yamada H, Takei K, Takeda T.
Biochem Biophys Res Commun. 2021 Jul 26;571:145-151. doi: 10.1016/j.bbrc.2021.07.041. - Ultracentrifugal separation, characterization, and functional study of extracellular vesicles derived from serum-free cell culture.
Hu HT, Nishimura T, Suetsugu S.
STAR Protoc. 2021 Jun 23;2(3):100625. doi: 10.1016/j.xpro.2021.100625. - The state of F-BAR domains as membrane-bound oligomeric platforms.
Snider CE, Wan Mohamad Noor WNI, Nguyen NTH, Gould KL, Suetsugu S.
Trends Cell Biol. 2021 Aug;31(8):644-655. doi: 10.1016/j.tcb.2021.03.013. Epub 2021 Apr 20 ;Review. - Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells.
Nishimura T, Oyama T, Hu HT, Fujioka T, Hanawa-Suetsugu K, Ikeda K, Yamada S, Kawana H, Saigusa D, Ikeda H, Kurata R, Oono-Yakura K, Kitamata M, Kida K, Hikita T, Mizutani K, Yasuhara K, Mimori-Kiyosue Y, Oneyama C, Kurimoto K, Hosokawa Y, Aoki J, Takai Y, Arita M, Suetsugu S.
Dev Cell. 2021 Mar 22;56(6):842-859.e8. doi: 10.1016/j.devcel.2021.02.029.
プレスリリース English - Regulation of caveolae through cholesterol-depletion-dependent tubulation mediated by PACSIN2.
Gusmira A, Takemura K, Lee SY, Inaba T, Hanawa-Suetsugu K, Oono-Yakura K, Yasuhara K, Kitao A, Suetsugu S.
J Cell Sci. 2020 Oct 12;133(19):jcs246785. doi: 10.1242/jcs.246785.
Featured in the in this issue.
First Author Interview. - The roles of the diversity of amphipathic lipids in shaping membranes by membrane-shaping proteins.
Kitamata M, Inaba T, Suetsugu S.
Biochem Soc Trans. 2020 Jun 29:BST20190376. doi: 10.1042/BST20190376. - Spatiotemporal Analysis of Caveolae Dynamics Using Total Internal Reflection Fluorescence Microscopy.
Senju Y, Suetsugu S.
Methods Mol Biol. 2020;2169:63-70. doi: 10.1007/978-1-0716-0732-9_6. - The membrane binding and deformation property of vaccinia virus K1 ankyrin repeat domain protein.
Kitamata M, Hotta M, Hamada-Nakahara S, Suetsugu S.
Genes Cells. 2020 Mar;25(3):187-196. doi: 10.1111/gtc.12749. - PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly.
Nguyen LP, Tran SC, Suetsugu S, Lim YS, Hwang SB.
J Virol. 2020 Feb 14;94(5):e01531-19. doi: 10.1128/JVI.01531-19. - Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7.
Hanawa-Suetsugu K#, Itoh Y#, Ab Fatah M#, Nishimura T#, Takemura K, Takeshita K, Kubota S, Miyazaki N, Wan Mohamad Noor WNI, Inaba T, Nguyen NTH, Hamada-Nakahara S, Oono-Yakura K, Tachikawa M, Iwasaki K, Kohda D, Yamamoto M, Kitao A, Shimada A, Suetsugu S. (# equal contribution)
Nat Commun. 2019 Oct 18;10(1):4763. doi: 10.1038/s41467-019-12738-w.
プレスリリース English - Membrane-Deformation Ability of ANKHD1 Is Involved in the Early Endosome Enlargement.
Kitamata M, Hanawa-Suetsugu K, Maruyama K, Suetsugu S.
iScience. 2019 Jun 18;17:101-118. doi: 10.1016/j.isci.2019.06.020.
プレスリリース English - PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking.
Dewi Pamungkas Putri D, Kawasaki T, Murase M, Sueyoshi T, Deguchi T, Ori D, Suetsugu S, Kawai T.
J Biol Chem. 2019 May 24;294(21):8412-8423. doi: 10.1074/jbc.RA118.005731. Epub 2019 Apr 3. - Membrane re-modelling by BAR domain superfamily proteins via molecular and non-molecular factors.
Nishimura T, Morone N,Suetsugu S
Biochem Soc Trans. 2018 Apr 17;46(2):379-389. doi: 10.1042/BST20170322. Epub 2018 Mar 14. Review. - Measurement of caveolin-1 densities in the cell membrane for quantification of caveolar deformation after exposure to hypotonic membrane tension.
Tachikawa M, Morone N, Senju Y, Sugiura T, Hanawa-Suetsugu K, Mochizuki A, Suetsugu S.
Sci Rep. 2017 Aug 10;7(1):7794. doi: 10.1038/s41598-017-08259-5. - Salt Bridge Formation between the I-BAR Domain and Lipids Increases Lipid Density and Membrane Curvature.
Takemura K, Hanawa-Suetsugu K, Suetsugu S, Kitao A.
Sci Rep. 2017 Jul 28;7(1):6808. doi: 10.1038/s41598-017-06334-5. - PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease.
Dumont V, Tolvanen TA, Kuusela S, Wang H, Nyman TA, Lindfors S, Tienari J, Nisen H, Suetsugu S, Plomann M, Kawachi H, Lehtonen S.
FASEB J. 2017 Sep;31(9):3978-3990. doi: 10.1096/fj.201601265R. Epub 2017 May 26. - Yeast Ivy1p Is a Putative I-BAR-domain Protein with pH-sensitive Filament Forming Ability in vitro.
Itoh Y, Kida K, Hanawa-Suetsugu K, Suetsugu S.
Cell Struct Funct. 2016 Feb 16;41(1):1-11. doi: 10.1247/csf.15014. Epub 2015 Dec 9. - Higher-order assemblies of BAR domain proteins for shaping membranes.
Suetsugu S.
Microscopy (Oxf). 2016 Jun;65(3):201-10. doi: 10.1093/jmicro/dfw002. Epub 2016 Feb 15. Review. - Protein kinase C (PKC)-mediated phosphorylation of PACSIN2 triggers the removal of caveolae from the plasma membrane.
Senju Y, Rosenbaum E, Shah C, Hamada-Nakahara S, Itoh Y, Yamamoto K, Hanawa-Suetsugu K, Daumke O, Suetsugu S.
J Cell Sci 2015 128:2766-2780; Advance Online Article June 19, 2015, doi:10.1242/jcs.167775
Featured in the in this issue’.
The image is the trajectories of caveolae under TIRF. - Possible regulation of caveolar endocytosis and flattening by phosphorylation of F-BAR domain protein PACSIN2/Syndapin II.
Senju Y, Suetsugu S.
Bioarchitecture. 2015 Dec 2;5(5-6):70-7. doi: 10.1080/19490992.2015.1128604. - TRPV4イオンチャネルのアンキリンリピート ドメインとPI(4,5)P2の相互作用による新たな制御機構末次志郎, 高橋重成, 伊藤弓弦, 竹村和浩, 嶋田 睦, 北尾彰朗, 森 泰生 生物物理 55(5),262-265(2015) DOI: 10.2142/biophys.55.262
- Dynamic Shaping of Cellular Membranes by Phospholipids and Membrane-Deforming Proteins.
Suetsugu S, Kurisu K, Takenawa T
Physiological Reviews, Oct;94(4):1219-1248. - TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2.
Takahashi N, Hamada-Nakahara S, Itoh Y, Takemura K, Shimada A, Ueda Y, Kitamata M, Matsuoka R, Hanawa-Suetsugu K, Senju Y, Mori MX, Kiyonaka S, Kohda D, Kitao A, Mori Y, Suetsugu S.
Nat Commun. 2014 Sep 26;5:4994. doi: 10.1038/ncomms5994.
プレスリリース 報道: NHK奈良９／２６、産経Web９／２９、日刊工業新聞９／３０、奈良新聞１０／４、日経産業新聞１０／２９ - Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells.
Ueyama T, Sakaguchi H, Nakamura T, Goto A, Morioka S, Shimizu A, Nakao K, Hishikawa Y, Ninoyu Y, Kassai H, Suetsugu S, Koji T, Fritzsch B, Yonemura S, Hisa Y, Matsuda M, Aiba A, Saito N.
J Cell Sci. 2014 May 1;127(Pt 9):2040-52. doi: 10.1242/jcs.143602. Epub 2014 Mar 7. - 細胞膜形態形成に関わるタンパク質と細胞骨格制御の研究
末次志郎
生化学第８６巻第５号，pp. ６３７―６４９（２０１４） - ドキ★ワク先端科学「細胞包む”シャボン玉”」
読売新聞寄稿連載 奈良県版 2014年9月30日
Molecular Medicine and Cell Biology
