研究業績

Publications

 

Research articles

  1. Ogura N, Sasagawa Y, Ito T, Tameshige T, Kawai S, Sano M, Doll Y, Iwase A, Kawamura A, Suzuki T, Nikaido I, Sugimoto K, Ikeuchi M*. 

    WUSCHEL-RELATED HOMEOBOX 13 suppresses de novo shoot regeneration via cell fate control of pluripotent callus. Science Advances 2023, doi: 10.1126/sciadv.adg6983

    ・press release: Study uncovers the secrets of plant regeneration

    ・プレスリリース：芽を生み出すかどうか、植物カルス細胞の分化を運命づける因子を突き止めた 植物の器官再生能力を制御する新たな仕組みを発見～農作物の組織培養効率を飛躍的に改善する技術開発に期待～

  2. Tanaka H, Hashimoto N, Kawai S, Yumoto E, Shibata K, Tameshige T, Yamamoto Y, Sugimoto K, Asahina M, Ikeuchi M*. Auxin-induced WUSCHEL-RELATED HOMEOBOX13 mediates asymmetric activity of callus formation upon cutting. Plant and Cell Physiology 2022 Oct 20:pcac146. doi: 10.1093/pcp/pcac146
    ・プレスリリース：植物が切断されても、傷口を修復してつなげる仕組みを解明 オーキシンが再生遺伝子を活性化して細胞塊形成 接ぎ木など園芸や食料増産に期待

  3. Lambolez A, Kawamura A, Takahashi T, Rymen B, Iwase A, Favero DS, Ikeuchi M, Suzuki T, Cortijo S, Jaeger KE, Wigge PA, Sugimoto K. Warm temperature promotes shoot regeneration in Arabidopsis thaliana. Plant and Cell Physiology 2022, doi: 10.1093/pcp/pcac017.

  4. Ikeuchi M*, Iwase A, Ito T, Tanaka H, Favero DS, Kawamura A, Sakamoto S, Wakazaki M, Tameshige T, Fujii H, Hashimoto N, Suzuki T, Hotta K, Toyooka K, Mitsuda N, Sugimoto K. Wound-inducible WUSCHEL RELATED HOMEOBOX 13 is required for callus growth and organ reconnection. Plant Physiology 2021, doi: 10.1093/plphys/kiab510
    ・プレスリリース：植物の組織修復と接ぎ木における器官再接着に必要な転写因子を発見

  5. Iwase A, Kondo Y, Laohavisit A, Takebayashi A, Ikeuchi M, Matsuoka K, Asahina M, Mitsuda N, Shirasu K, Fukuda H, Sugimoto K. WIND transcription factors orchestrate wound-induced callus formation, vascular reconnection and defense response in Arabidopsis. New Phytologist 2021, 232: 734-752.

  6. Morinaka H, Mamiya A, Tamaki H, Iwamoto A, Suzuki T, Kawamura A, Ikeuchi M, Iwase A, Higashiyama T, Sugimoto K, Sugiyama M. Transcriptome Dynamics of epidermal reprogramming during direct shoot regeneration in Torenia fournieri. Plant and Cell Physiology 2021 doi: 10.1093/pcp/pcab101.

  7. Coleman D, Kawamura A, Ikeuchi M, Favero DS, Lambolez A, Rymen B, Iwase A, Suzuki T, Sugimoto K. The SUMO E3 ligase negatively regulates shoot regeneration. Plant Physiology 2020, 184: 330-344.

  8. Rymen B, Kawamura A, Lambolez A, Inagaki S, Tekabayashi A, Iwase A, Sakamoto Y, Sako K, Favero DS, Ikeuchi M, Suzuki T, Seki M, Kakutani T, Roudier F, Sugimoto K. Histone acetylation orchestrates wound-induced transcriptional activation and acellular reprogramming in Arabidopsis. Communications Biology 2019, 2: 404.

  9. Amano R, Nakayama H, Momoi R, Omata E, Gunji S, Takebayashi Y, Kojima M, Ikematsu S, Ikeuchi M, Iwase A, Sakamoto T, Kasanhara H, Sakakibara H, Ferjani A, Kimura S. Molecular basis for natural vegetative propagation via regeneration in North American lake cress, Rorippa aquatica (Brassicaceae) Plant and Cell Physiology 2019, doi: 10.1093/pcp/pcz202.

  10. Ikeuchi M, Shibata M, Rymen B, Iwase A, Bågman AM, Watt L, Coleman D, Favero DS, Takahashi T, Ahnert SE, Brady SM, Sugimoto K. A gene regulatory network for cellular reprogramming in plant regeneration. Plant and Cell Physiology 2018, 59: 765-777.

  11. Ikeuchi M*, Iwase A, Rymen B, Lambolez A, Kojima M, Takebayashi Y, Heyman J, Watanabe S, Seo M, De Veylder L, Sakakibara H, Sugimoto K. Wounding triggers callus formation via dynamic hormonal and transcriptional changes in Arabidopsis. Plant Physiology 2017, 175: 1158-1174.

  12. Iwase A, Harashima H, Ikeuchi M, Rymen B, Ohnuma M, Komaki S, Morohashi K, Kurata T, Nakata M, Ohme-Takagi M, Grotewold E, Sugimoto K. WIND1 promotes shoot regeneration through transcriptional activation of ESR1 in Arabidopsis. Plant Cell 2017, 1:54-69.

  13. Ikeuchi M, Iwase A, Rymen B, Harashima H, Shibata M, Ohnuma M, Breuer C, Morao AK, de Lucas M, De Veylder L., Goodrich J, Brady SM, Roudier F, Sugimoto K. PRC2 represses dedifferentiation of mature somatic cells in Arabidopsis. Nature Plants 2015, 1:15089.

  14. Iwase A, Mita K, Nonaka S, Ikeuchi M, Koizuka C, Ohnuma M, Ezura H, Imamura J, Sugimoto K (2015) WIND1-based acquisition of regeneration competency in Arabidopsis and rapeseed. Journal of Plant Research 2015, 128:389-397.

  15. Ikeuchi M, Igarashi H, Okada K, Tsukaya H. Acropetal leaflet initiation of Eschscholzia californica is achieved by constant spacing of leaflets and differential growth of leaf. Planta 2014, 240: 125-135.

  16. Ikeuchi M, Tatematsu K, Yamaguchi T, Okada K, Tsukaya H. Precocious progression of tissue maturation instructs basipetal initiation of leaflets in Chelidonium majus asiaticum (Papaveraceae). American Journal of Botany 2013, 100: 1-11.

  17. Iwase A, Mitsuda N, Ikeuchi M, Ohnuma M, Koizuka C, Kawamoto K et al. Arabidopsis WIND1 induces callus formation in rapeseed, tomato, and tobacco. Plant Signaling Behavior 2013, 8, e27432

  18. Ikeuchi M, Yamaguchi T, Kazama T, Ito T, Horiguchi G, Tsukaya H. ROTUNDIFOLIA4 regulates cell proliferation along the body axis in Arabidopsis shoot. Plant and Cell Physiology 2011, 52: 59-69.

  19. Nagano AJ, Fukazawa M, Hayashi M, Ikeuchi M, Tsukaya H, Nishimura M. AtMap1: a DNA microarray for genomic deletion mapping in Arabidopsis thaliana. Plant Journal 2008, 56: 1058-1065.

  20. Tsukaya H, Tsujino R, Ikeuchi M, Isshiki Y, Kono M, Takeuchi T et al. Morphological variation in leaf shape in Ainsliaea apiculata with special reference to the endemic characters of populations on Yakushima Island, Japan. Journal of Plant Research 2007, 120: 351-358.


  Review

  1. Chen C, Hu Y, Ikeuchi M, Jiao Y, Prasad K, Su YH, Xiao J, Xu L, Yang W, Zhao Z, Zhou W, Zhou Y, Gao J, Wang JW. Plant regeneration in the new era: from molecular mechanisms to biotechnology applications. Sci China Life Sci. 2024 67:1338-1367. doi: 10.1007/s11427-024-2581-2.

  2. Ikeuchi M*. Breaking the spatial restriction of pluripotency acquisition by environmental stimuli. Molecular Plant 2022 Nov 26:S1674-2052(22)00433-6. doi: 10.1016/j.molp.2022.11.014.

  3. Umeda M, Ikeuchi M, Ishikawa M, Ito T, Nishihama R, Kyozuka J, Torii UK, Satake A, Goshima G, Sakakibara H. Plant stem cell research is uncovering the secrets of longevity and persistent growth. Plant Journal 2021, doi: 10.1111/tpj.15184.

  4. Ikeuchi M*, Rymen B, Sugimoto K. How to plants transduce wound signals to induce tissue repair and organ regeneration? Current Opinion in Plant Biology. 2020, 57: 72-77.

  5. Ikeuchi M, Favero S, Sakamoto Y, Iwase A, Coleman D, Rymen B, Sugimoto K*. Molecular mechanisms of plant regeneration. Annual Review of Plant Biology 2019, 70: 377-406

  6. Ikeuchi M*, Rhodes J. Latest advances in plant development and environmental response, the inaugural Cold Spring Harbor Asia Plant Biology meeting in Japan. Plant and Cell Physiology 2017, 58: 1286-1290.

  7. Ikeuchi M, Ogawa Y, Iwase A, Sugimoto K. Plant regeneration: cellular origins and molecular mechanisms. Development 2016, 143: 1442-1451.

  8. Ikeuchi M, Iwase A, Sugimoto K. Control of plant cell differentiation by histone modification and DNA methylation. Current Opinion in Plant Biology 2015, 28: 60-67.

  9. 池内桃子, 岩瀬哲, 杉本慶子：“傷付いた植物はどのように修復・再生するのか”BSJ review, 2015

  10. 岩瀬哲, 池内桃子, 杉本慶子：“カルス形成の分子メカニズム〜アクセル因子とブレーキ因子〜” BSJ review, 2015

  11. Ikeuchi M, Sugimoto K, Iwase A. Plant callus: mechanisms of induction and repression. Plant Cell 2013, 25: 3159-3173.

  12. Yamaguchi T, Ikeuchi M and Tsukaya H. (2013) ROTUNDIFOLIA4. In: Handbook of biologically active peptides, pp53-57