新学術領域研「植物多能性幹細胞」

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Research Outline


Research on “Stem Cell Proliferation” (A01)
We aim to understand the control system giving rise to plant forms exhibiting modularity as a result of the regulated genesis of stem cell populations. We will analyze the schemes of asymmetric cell division needed for genesis and maintenance of plant stem cells, and the mechanisms by which differentiated cells are reprogrammed to generate stem cells, and clarify the machinery, transcriptional control network, and chromatin structure control necessary for stem cell production. In addition, we will clarify the systems for biosynthesis and transport of the plant hormones which control stem cell division, and the signaling molecules which regulate the timing of stem cell genesis, thereby gaining an understanding of the temporal and spatial control systems giving rise to stem cells.

Research on “Maintenance of Stem Cell Characteristics” (A02)
We aim to understand the control systems which allow maintenance of stem cell pluripotency and genome homeostasis, and enable indefinite organogenesis. We hope to understand the molecular mechanisms behind maintenance of stem cell pluripotency by focusing on permanent and transitory stem cells in plants. In addition, we will clarify the mechanisms protecting genome stability, while also clarifying the mechanisms which allow genomic changes in stem cells, giving rise to a full array of diversity.

Plant Stem Cell Analysis Center
We aim to understand the control systems which allow maintenance of stem cell pluripotency and genome homeostasis, and enable indefinite organogenesis. We hope to understand the molecular mechanisms behind maintenance of stem cell pluripotency by focusing on permanent and transitory stem cells in plants. In addition, we will clarify the mechanisms protecting genome stability, while also clarifying the mechanisms which allow genomic changes in stem cells, giving rise to a full array of diversity.