機能ゲノム医学研究室(石田研究室)
Functional Genomics and Medicine

論文リスト Publications

それでもわれわれが PD-1 を捨てられない理由
石田靖雅
実験医学 36 巻 9 号、p1452-1456, 2018

Collection of homozygous mutant mouse embryonic stem cells arising from autodiploidization during haploid gene trap mutagenesis.
Yamanishi A, Matsuba A, Kondo R, Akamatsu R, Tanaka S, Tokunaga M, Horie K, Kokubu C, IshidaY, Takeda J.
Nucleic Acids Res. 2018 (doi: 10.1093/nar/gky183)

PD-1 による免疫学的「自己」の再定義
石田靖雅
ファルマシア 53 巻 10 号、p967-969, 2017

PD-1 の発見について語るときに私の語ること
石田靖雅
現代化学 通巻 551 号、p24-27, 2017

CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells.
Kotoku T, Kosaka K, Nishio M, Ishida Y, Kawaichi M, and Matsuda E.
Sci. Rep. 23, 6, 34188, 2016

哺乳類の発生や分化におけるメチル化 DNA 結合タンパク質の役割
松田永照、西尾美紀、石田靖雅
Bio Clinica 31 巻 5 号、p79-84, 2016

Abnormal development of placenta in HtrA1-deficient mice.
Hasan MZ, Ikawati M, Tocharus J, Kawaichi M, and Oka C.
Dev. Biol. 397, 89-102, 2015

Integrin β1 controls VE-cadherin localization and blood vessel stability.
Yamamoto H, Ehling M, Kato K, Kanai K, van Lessen M, Frye M, Zeuschner D, Nakayama M, Vestweber D, Adams RH.
Nat Commun. 10;6:6429, 2015

新しい癌免疫療法 - PD-1 発見の経緯と研究の歴史 -
石田靖雅
THE LUNG perspectives 23 巻 4 号、p93-97, 2015

PD-1: 発見の経緯と研究の歴史
石田靖雅
Year Book of RCC 2014、p35-41, 2015

今明かす PD-1 発見の舞台裏
石田靖雅
細胞工学 33 巻 10 号、p1038-1041, 2014

HtrA1 is induced by oxidative stress and enhances cell senescence through p38 MAPK pathway.
Supanji, Shimomachi M, Hasan MZ, Kawaichi M, and Oka C.
Exp. Eye Res. 112, 79-92, 2013

Evidence that the Upf1-related molecular motor scans the 3'-UTR to ensure mRNA integrity.
Shigeoka T, Kato S, Kawaichi M, and Ishida Y.
Nucleic Acids Res.40, 6887-6897, 2012

Mixture of differentially tagged Tol2 transposons accelerates conditional disruption of a broad spectrum of genes in mouse embryonic stem cells.
Mayasari NI, Mukougawa K, Shigeoka T, Kawakami K, Kawaichi M, and Ishida Y.
Nucleic Acids Res. 40, e97, 2012

CtBP-interacting BTB zinc finger protein (CIBZ) promotes proliferation and G1/S transition in embryonic stem cells via Nanog.
Nishii T, Oikawa T, Ishida Y, Kawaichi M, and Matsuda T.
J. Biol. Chem. 287, 12417-24, 2012

The methyl-CpG-binding protein CIBZ suppresses myogenic differentiation by directly inhibiting myogenin expression.
Oikawa Y, Omori R, Nishi I, Ishida Y, Kawaichi M, and Matsuda E.
Cell Research 21, 1578-90, 2011

Proteasome activator PA28γ stimulates degradation of GSK3-phosphorylated insulin transcription activator MAFA.
Kanai K, Aramata S, Katakami S, Yasuda K, Kataoka K.
J Mol Endocrinol. 47(1):119-127, 2011

SUMOylation negatively regulates transcriptional and oncogenic activities of MafA.
Kanai K, Reza HM, Kamitani A, Hamazaki Y, Han SI, Yasuda K, Kataoka K.
Genes Cells. 1;15(9):971-82, 2010

Down-regulation of CIBZ, a novel substrate of caspase-3, induces apoptosis.
Oikawa Y, Matsuda E, Nishi T, Ishida Y, and Kawaichi M.
J. Biol. Chem. 283, 14242-47, 2008

Suppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cells.
Shigeoka T, Kawaichi M, and Ishida Y.
Nucleic Acids Res. 33, e20, 2005

Identification of a novel BTB-zinc finger transcriptional repressor, CIBZ, that interacts with CtBP corepressor.
Sasai N, Matsuda E, Sarashina E, Ishida Y, and Kawaichi M.
Genes to Cells 10, 871-85, 2005

Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis.
Tsuchiya A, Yano M, Tocharus J, Kojima H, Fukumoto M, Kawaichi M, and Oka C.
Bone 37, 323-336, 2005

NMD 経路の抑制による理想的な遺伝子トラップシステムの構築
重岡稔章、石田靖雅
細胞工学 24 巻 7 号、p729-733, 2005

NMD 経路の抑制による新しい遺伝子トラップシステムの構築
重岡稔章、石田靖雅
バイオテクノロジージャーナル 5 巻 4 号、p464-466, 2005

Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis.
Matsuda E, Shigeoka T, Iida R, Yamanaka S, Kawaichi M, and Ishida Y.
Proc. Natl. Acad. Sci. USA 101, 4170-4174, 2004

Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling.
Tocharus J, Tsuchiya A, Kajikawa M, Ueta Y, Oka C, and Kawaichi M.
Dev. Growth Differ. 46, 257-274, 2004

HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins.
Oka C, Tsujimoto R, Kajikawa M, Koshiba-Takeuchi K, Ina J, Yano M, Tsuchiya A, Ueta Y, Soma A, Kanda H, Matsumoto M, Kawaichi M.
Development 131, 1041-1053, 2004

RET: a poly A-trap retrovirus vector for reversible disruption and expression monitoring of genes in living cells.
Ishida Y, Leder P.
Nucleic Acids Res. 27, e35, 1999

Disruption of the Mouse RBP-J Kappa Gene Results in Early Embryonic Death. Oka C, Nakano T, Wakeham A, de la Pompa JL, Mori C, Sakai T, Okazaki S, Kawaichi M, Shiota K, Mak TW, Honjo T.
Development 121, 3291-301, 1995

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
Ishida Y, Agata Y, Shibahara K, and Honjo T.
EMBO J. 11, 3887-3895, 1992

 

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